Robrecht Raedt Selected Research

Kainic Acid (Kainate)

1/2022	White Matter Integrity in a Rat Model of Epileptogenesis: Structural Connectomics and Fixel-Based Analysis.
1/2022	Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model.
1/2021	Long-term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy.
10/2020	Exploring with [18F]UCB-H the in vivo Variations in SV2A Expression through the Kainic Acid Rat Model of Temporal Lobe Epilepsy.
1/2020	Kainic acid-induced status epilepticus decreases mGlu5 receptor and phase-specifically downregulates Homer1b/c expression.
1/2020	Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration.
11/2019	Alterations in the functional brain network in a rat model of epileptogenesis: A longitudinal resting state fMRI study.
3/2016	Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures.
1/2015	Vagus nerve stimulation has antidepressant effects in the kainic acid model for temporal lobe epilepsy.
11/2011	Automatic detection of epileptic seizures on the intra-cranial electroencephalogram of rats using reservoir computing.

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Robrecht Raedt Research Topics

Disease

30	Epilepsy (Aura) 01/2022 - 12/2003
23	Drug Resistant Epilepsy 04/2022 - 06/2006
19	Seizures (Absence Seizure) 01/2022 - 12/2005
15	Temporal Lobe Epilepsy 01/2022 - 08/2007
4	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022 - 11/2019
2	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 03/2020
2	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 08/2017
2	Cerebral Hemorrhage 01/2021 - 01/2020
2	Neoplasms (Cancer) 09/2020 - 03/2020
2	Hypothermia 11/2019 - 08/2017
2	Disease Progression 01/2019 - 06/2006
2	Heart Failure 01/2018 - 08/2017
2	Nervous System Diseases (Neurological Disorders) 08/2010 - 09/2005
1	Cognitive Dysfunction 01/2022
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 09/2020
1	Marfan Syndrome (Marfan's Syndrome) 09/2020
1	Cardiomyopathies (Cardiomyopathy) 09/2020
1	Inflammation (Inflammations) 03/2020
1	Hemorrhage 01/2020
1	Stroke (Strokes) 01/2020
1	Rheumatoid Arthritis 01/2018
1	Pain (Aches) 08/2017
1	Tinnitus 08/2017
1	Seroma 01/2016
1	Mental Disorders (Mental Disorder) 01/2015
1	Anhedonia 01/2015
1	Absence Epilepsy (Childhood Absence Epilepsy) 11/2011
1	Weight Loss (Weight Reduction) 09/2008

Drug/Important Bio-Agent (IBA)

12	Kainic Acid (Kainate)IBA 01/2022 - 09/2010
5	Pharmaceutical PreparationsIBA 01/2022 - 12/2005
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2011
5	Anticonvulsants (Antiepileptic Drugs)IBA 11/2019 - 06/2006
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2022 - 05/2011
3	Levetiracetam (Keppra)FDA LinkGeneric 01/2022 - 12/2005
3	Clozapine (Clozaril)FDA LinkGeneric 01/2022 - 11/2019
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2020
3	Adenosine (Adenocard)FDA LinkGeneric 06/2011 - 06/2010
2	Collagenases (Collagenase)FDA Link 01/2021 - 01/2020
2	Messenger RNA (mRNA)IBA 09/2020 - 01/2020
2	MedetomidineIBA 01/2020 - 11/2019
2	Urate Oxidase (Uricase)IBA 03/2016 - 01/2016
2	Uric Acid (Urate)IBA 03/2016 - 01/2016
2	Pilocarpine (Ocusert)FDA LinkGeneric 01/2016 - 05/2011
1	JHU37160IBA 01/2022
1	LigandsIBA 01/2022
1	Designer DrugsIBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2021
1	Amyloid beta-PeptidesIBA 01/2021
1	HemosiderinIBA 01/2021
1	Extracellular Matrix ProteinsIBA 09/2020
1	Fibrillin-1IBA 09/2020
1	Tumor Biomarkers (Tumor Markers)IBA 09/2020
1	RadiopharmaceuticalsIBA 03/2020
1	TurpentineIBA 03/2020
1	Glial Fibrillary Acidic ProteinIBA 01/2020
1	Coloring Agents (Dyes)IBA 01/2020
1	diazonaphthalenedisulfonic acid (NDS)IBA 01/2020
1	Dihydrotachysterol (AT 10)IBA 01/2020
1	cresyl violetIBA 01/2020
1	clozapine N-oxideIBA 11/2019
1	ElementsIBA 01/2019
1	Allopurinol (Remid)FDA LinkGeneric 03/2016
1	EnzymesIBA 01/2016
1	Pentylenetetrazole (Metrazol)IBA 01/2016
1	Antidepressive Agents (Antidepressants)IBA 01/2015
1	SaccharinIBA 01/2015
1	Neurotransmitter Agents (Neurotransmitter)IBA 05/2011
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 03/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2009
1	Interleukin-10 (Interleukin 10)IBA 09/2009
1	Interleukin-8 (Interleukin 8)IBA 09/2009
1	LipopolysaccharidesIBA 09/2009
1	CytokinesIBA 09/2009
1	Interleukin-6 (Interleukin 6)IBA 09/2009
1	CarbohydratesIBA 09/2008
1	Neuroprotective AgentsIBA 06/2006
1	PlasticsIBA 06/2006

Therapy/Procedure

26	Vagus Nerve Stimulation 04/2022 - 06/2006
16	Therapeutics 04/2022 - 06/2006
8	Deep Brain Stimulation 01/2020 - 12/2003
7	Electrodes (Electrode) 12/2020 - 12/2003
1	Aftercare (After-Treatment) 01/2022
1	Radiotherapy 01/2022
1	Stroke Rehabilitation 01/2018
1	Transcranial Magnetic Stimulation 01/2016
1	Drug Therapy (Chemotherapy) 01/2015
1	Ketogenic Diet 03/2014
1	Investigational Therapies (Experimental Therapy) 11/2010
1	Cannula 09/2010
1	Cell Transplantation 12/2009
1	High-Protein Low-Carbohydrate Diet (Atkins Diet) 09/2008
1	Cell- and Tissue-Based Therapy (Cell Therapy) 09/2005